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Presence of both anaemia and eosinophilia in the early stage of hookworm infection inourstudy –anextremely importantfinding

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Author: 
Govindarajalu Ganesan
Abstract: 

Objective: Many studies have shown the presence of anaemia in hookworm infection. Many studies have also shown the presence of eosinophilia in hookworm infection. But so far detailed study was not done to know about the occurence of bothanaemia and eosinophiliain patients with early stage of hookworm infection found while doing upper gastro-intestinal endoscopy. Hence adetailed study was done to know about the occurence of both anaemia and eosinophiliain patients with early stage of hookworm infection found while doing upper gastro-intestinal endoscopy.
Methods: A study of 1137 patients who had under gone upper gastro-intestinal endoscopy for a period of four years and eight months from May 2009 to December2013 was carried out. In each of these 1137 patients, the first and second part of duodenum were carefully examined to find out the presence of hookworms. In all the patients found to have hookworm sin duodenum, investigations were done to know about the presence or absence of anaemia and the presence or absence of eosinophilia. The results were found as given below.
Results: Out of these 1137patients, 14 patients found to have hookworms in duodenum while doing upper gastro-intestinal endoscopy were taken into consideration for our study. Out of these14 patients with hookworms in duodenum, 9 patients hadanaemia and 6 of these 9 patients were found to have mild anaemia indicatingearly stage of hookworm infection. Out of these 6 patients with mild anaemia in early stage of hookworm infection, 4patientsalsohad eosinophilia.
Conclusion: Four patients with mild anaemia in the early stage of hookworm infection also had eosinophilia. Hence in addition to mild anaemia in the early stage of hookworm infection eosinophilia is another important indicator of hookworm infection.

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