The two major problems: climate change and global population are now common in worldwide. According to UNDESA 2017, there will be 10 billion global populations within 2050 and more desiccation will be observed with rising temperatures. It will likely have negative consequences on crop growth and productivity worldwide. Chemical fertilizers are imperative resource of plant nutrition, but quite expensive, representing a source of environmental pollution. Increasing restrictions on pesticide application in agricultural food products indicate urgent need for safer alternatives to maintain the product quality and restrain pathogen infections. Recent alternatives to chemical fertilizers and pesticides improve crop growth, using a promising and eco-friendly plant biostimulants. Thus plant fitness enhances. The need of fertilizers will be reduced, also resistance to abiotic stresses. Our study aimed to apply Moringa leaf extract (MLE) on seedlings of Cucurbita plant to acclimate and tolerate further heat stress exposition as a pre-treatment. MLE was applied in 5 plants as foliar spray (FS). The results showed that all treatments significantly increased plant vegetative growth, recommending higher yield grown in MLE. Plant extract could potentially provide a safe alternative to chemical fertilizers and plant regulators. Our experimental study indicates that MLE significantly improve growth of the plant alleviating the abiotic stress.