This study was done to assess the drug use pattern among pregnant women and to evaluate the impact of clinical pharmacist mediated counselling on medication adherence by providing regular patient education regarding pregnancy and precautions recommended to prevent the complications in the later stages. A consent was taken from each pregnant women who were voluntarily enrolled in the study. The prescriptions possessing at least two or more drugs were analyzed. The drugs prescribed and taken by the pregnant women were considered based on their pharmacological class. Analysis of prescription patterns did not show the use of any drugs that should not be prescribed during pregnancy. Majority of the drugs prescribed belonged to vitamins, minerals and nutrients which play a very major role in foetal development. During the study, medication adherence of the pregnant women was assessed and the impact of counselling on adherence was seen. There is an increase in the rate of adherence in the pregnant women during their first and second follow-ups when compared with their baseline medication adherence. Pregnant women are counselled and educated regarding the advantages and disadvantages of various drug used during pregnancy. Thus the monitoring of prescription and drug utilization studies can identify the problems and provide feedback to prescribers so as to create awareness about irrational use of drugs. The impact of self-medication and other alternative therapies should also be explained to pregnant women and educating regarding the advantages and disadvantages and to identify the drawbacks of non adherence among them.