The generation and treatment of the wastewater has become an important health issue in the developing countries due to inadequate facilities for treatment (Singh et al., 2015). About 80% of the water supply used by human society comes as municipal wastewater in sewer system as sewage (Sinha et al., 2008). In the present study an attempt has been made to assess the efficacy of vermifiltration of the wastewater collected from the drainage canal of Burla town, Sambalpur. The analysis was carried out by considering certain physico-chemical parameters like pH, electrical conductivity, TSS, BOD, COD, nitrate, fluoride, chloride which is considered indicators of the pollution loads in the wastewater. The study revealed that there was significant reduction of the various physico-chemical parameters on vermifiltration. There was significant reduction with respect to the duration of retention of the wastewater in the vermibed. There was reduction of pH, Electrical Conductivity, TSS, BOD, COD, Nitrate, Fluoride and Chloride by 1.2%, 36.9%, 40.3%, 60.5%, 44.4%, 47.2%, 39.7% and 55.1%, respectively by 30th day. The vermifitered water was odour free.