The aim of this study was to investigate the respiratory affections in goats with special reference to bacterial infections through bacteriological techniques and MALDI-TOF. A total of 192 swabs from trachea and inner core of lung were collected aseptically. The generated data was basically pertaining to 60 died goats and 154 slaughtered goats which were screened during present study by bacteriological techniques and MALDI-TOF. After thorough post mortem examination of screened carcasses of goats, 192 amongst 214 were with either or mixed type of gross lesion targeting either or multiple organs of respiratory system. The overall prevalence of respiratory affections in screened goats having gross respiratory affections was found to be 89.72%. Staphylococcus species found to be highly prevalent than other bacterial Species recorded. The overall prevalence of respiratory affections in screened goats was found to be 89.72%. The goats aging 1 year showed 96.91% prevalence and goats ageing more than 1 year were with 71.92% prevalence of respiratory affections. Staphylococcus species found to be highly prevalent than other bacterial Species.