AIM: Objective of the study is to evaluate the outcome of labor of premature rupture of membranes in mature vertex pregnancy regarding mode of delivery, latent period following PROM, maternal morbidity, infant morbidity and mortality, and influence of latent period on maternal morbidity, infant morbidity and mortality and to compare the outcome of primigravida with multigravida. MATERIALS AND METHODS: This study was conducted in the department of obstetrics and gynecology, in labour room of GOVT GENERAL HOSPITAL, KAKINADA, affiliated to Rangaraya medical college from nov 2011 to oct 2013. This study was done on 150 cases of premature rupture of membranes, with vertex presentation on mature pregnancy i.e., 37 weeks onwards. RESULTS: Among 150 cases, 110 cases (73.3%) delivered vaginally. The incidence of cesarean section is 21.3% in primigravida with PROM and 17.3% in multigravida with PROM. Latent period, elapsed period, and PROM delivery interval are shorter in multigravida compared to primigravida. The incidence of maternal morbidity, and infant morbidity and mortality is more with a longer latent period. CONCLUSION: Though mode of delivery is vaginal in majority of the cases, incidence of caesarean section is slightly higher in primigravidae compared to multigravidae. However, PROM is not the indication per se in most of the cases. The outcome of labor in PROM in mature vertex pregnancy is favourable to multigravida compared to primigravida. Thus, primigravida with PROM needs more attention. With active management of premature rupture of membranes in mature vertex pregnancy, latent period, elapsed period and PROM delivery interval can be shortened, thus reducing the maternal morbidity, infant morbidity and mortality.