The COVID-19 pandemic started in 2019, and multiple public health preventive measures have been taken, such as PCR tests preoperatively and for pre-and post-travel requirements. However, preventive health services have faced different dilemmas, particularly the issue of false-positive PCR test results, which were confirmed as the repeated tests were negative. People face different consequences after a positive PCR test result, such as postponing surgery, absence from work, and financial problems, all of which negatively impact people’s lives. Health care practitioners working in preventive medicine and public health departments bear the brunt of the anger from patients when they encounter such cases. Therefore, there is a need for a fixed guideline regarding the false positive swabs and how to clear the person from isolation when all criteria suggest the person is no longer contagious.