Three hundred one-day old Ven-Cobb straight run commercial broiler chicks were supplemented with the non starch polysaccharide hydrolyzing enzymes at 1X higher concentration (HC) viz. (xylanase, ß-D-glucanase, cellulase, mannanase and pectinase @ 2400, 4800, 1800, 4800, and 2400 IU/kg respectively. The similar enzyme combination was supplemented @ 4800,9600,3600,9600 and 4800 IU/kg respectively as 2X (HC) to the corn + soybean meal based diets having sub-optimal (-100 Kcal) energy levels. Similarly the diets were supplemented with NSP hydrolyzing enzymes at 1X lower concentrations (LC) viz. (xylanase, ß-D-glucanase, cellulase, mannanase and pectinase @ 400, 240, 200, 200, and 400 IU/kg respectively. The same NSP hydrolyzing enzyme combination was supplemented @ 800,480,400,400 and 800 IU/Kg respectively as 2X (LC). The birds were weighed, wing banded and randomly distributed in to six experimental groups, with ten replicates and five birds in each replicate to assess the effect of the NSPHE combination on growth performance of broilers. The NSP hydrolyzing enzyme supplemented diet @ 2X (HC) had shown significantly higher (P<0.05) BWG in week wise the feed intake was significantly higher (P<0.05) in standard control diet and NSP hydrolyzing enzyme supplemented diet @ 2X (HC) respectively. Supplementation of NSP enzymes had influenced the FCR (P<0.05) in broilers when reared on the sub-optimal diets.