This study examined the epidemiology of Salmonella Typhi in Kala'a Hong Local Government Area, Adamawa State. The research aimed to identify the prevalence, distribution, and risk factors associated with Salmonella Typhi infections within the region. A cross-sectional survey design was employed, with samples collected from both clinical and environmental sources across selected communities. Laboratory analyses confirmed the presence of Salmonella Typhi, with results indicating a significant prevalence rate among the population. The results also revealed that the age 56-60 has the highest prevalence of Salmonella typhi followed by age group 26-30,41-45 and 46-50 had 83.3% and the least is in age group of 36-40,51-55. Based on gender the female has the highest prevalence of salmonella typhi while the male has the lowest. The study further explored demographic variables, hygiene practices, and environmental conditions contributing to the spread of the infection. The findings revealed a correlation between inadequate sanitation, poor water quality, and the high incidence of Salmonella Typhi infections. The study concluded that enhanced public health measures, including improved sanitation and awareness campaigns, are crucial in mitigating the spread of Salmonella Typhi in Hong Local Government Area. The researcher recommend that policy intervention and further research should be carry out in the study area.
