Diabetes mellitus is a chronic degenerating disease which is worldwide occurrence with continuous upward trend in the societies. It has become very difficult to manage owing to its complexity. This disease was long been treated with diet, herbs and herbo-mineral compound long before the era of synthetic hypoglycemic drugs, many of which were fond efficacious as investigated both clinically and experimentally by various research workers. In Ayurvedic classics a good number of single herbs and a number of compound preparations are mentioned – like Aragwadhadi, Salsaradi, Mustakadi, Triphaladi, Trapvadi gana etc. for the management of Diabetes mellitus in various classical texts. The drugs are detailed enumerated in this paper for the references so available in Charaka Samhita, Sushruta Samhita and Astanga Samgraha specially. However, it can pave the way for researcher in future for validation of the concept if any.