Pena Indigofera suffruticosa belongs to the Fabaceae family and stands out among the genus for its pharmacological properties. A literature review was carried out based on 30 articles taken from databases in virtual libraries such as Lilacs, Pubmed, Scielo, and Science Direct, in order to verify the traditional uses, biological activities, and phytochemistry of Indigofera suffruticosa. Its biological activities were evaluated: anti-inflammatory, embryotoxic, antimicrobial, and antitumor. This range of already demonstrated phytotherapeutic properties means it is a plant with great therapeutic potential and its properties can assist in various studies.