The study of basins to attempt to assess the impact to land use change has a long history from last one hundred years. Since the twentieth century, the frequency of global flood disaster has been higher than any time before one of the important reason is land use/land cover change by human activities. The major change in land use the affect hydrology are afforestation and deforestation, the intensification of agriculture, the drainage of wetlands, road construction, and urbanization (De Roo et al., 2001). The main objectives of the study are to assess the land use pattern in Ambala district from 2001 to 2011, to demarcate the area of vulnerability and appreciate effect of flood and to prepare a flood hazard zone in Ghaggar river map through remote sensing and GIS techniques. Urban occupied 2.94 percent of the study area in 2001 which has increases a total of 3.69 percent in 2011 showing net increase of 0.75 percent with an annual rate of increase of 118.189 ha area. Rivers have decreased from 5523.08 ha in 2001 to 5022 in 2011. River occupied 3.51 percent of the study area in 2001 which has decrease a total of 3.19 percent in 2011 showing a net decrease of -0.32 percent with an annual rate of decrease of 50.18 ha area. Flood risk zone were delineated by grouping the polygons of the integrated layer in to different risk zone. Create buffer utility of ARC/Map was used to create buffer zones around the river. Agriculture being the dominant activity in whole of the Ambala district has got maximum area under 500m high sensitive buffer zone. River having their area from 2001 to 2011 recorded growth of 509.87 ha under low sensitive flood prone zone.