Multifunctional excipients are also called all-in-one excipients and are made using co-processing technology. Co-processing is a way to enhance individual excipient physical properties like bulk density, texture, particle size, flowability, and functionality like tablet hardness, weight uniformity, drug uniformity, disintegration, and dissolution profile. BARETab® SL is a multifunctional excipient made by using co-processing technology, and specially developed for poor water-soluble active ingredients, we have manufactured a Hydrochlorothiazide tablet using BARETab® SL and individual excipient, evaluated pre-compression and post-compression parameters parallelly evaluate multifunctional and individual excipient physical and morphological properties. Multifunctional excipients BARETab® SL have outstanding physical properties and tablet properties, it gives higher tablet hardness, lower disintegration time, and enhanced poor soluble API solubility.
MULTIFUNCTIONAL EXCIPIENTS PERFORMANCE EVALUATION INTO POOR WATER-SOLUBLE DRUGS HYDROCHLOROTHIAZIDE IN ORAL SOLID DOSAGE FORMS
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