The aim of the study was to assess the demographic profile and drug compliance of Type 2 diabetic (T2DM) patients attending tertiary care centre. A descriptive study design was adopted. A total of 100 participants were selected using convenient sampling. The structured interview schedule was used to collect data from samples by using modified diabetic drug compliance scale of 10 day recall method. As a result, out of 100 samples, majorities (37%) of them were in the age group of 51-60 years and 4% of them were in the age group of 21-30 years. 88% of them were adherent to 75-100% medications and 12% of them were adherent to 50-75% of medications. Elders, employed, urban area of residence, normal BMI, and less than 3 years duration of diabetes were associated with more drug compliance score among type 2 diabetic patients. In conclusion, the medication adherence in diabetes is critically important for maximizing the effectiveness of drug therapy and in prevention of early diabetic complications. Health Education or strategies towards the improvement of medication adherence among (T2DM) patients are highly essential.