SARS-CoV-2 is the causative agent of COVID -19 that is declared a global pandemic by the WHO in 2020.COVID-19 is transmitted by aerosol particle and close contact through the sneezing and coughing. Till date no effective treatment is present for its management. This review is from different article for usefull therapeutic for COVID -19. Aim of Study;. Infection of COVID -19 to the patients and its management in gospital in general ward and intensive care unit. Methods: A systematic review was developed on based of screening of different research article, review article, Guidline and case profile that all are selected from electronic media from Google and Pub med. After full screening and review from article after downloading from Google the some therapeutic agents are decided for management of COVID-19 infected patient. Result: The initial manuscripts identified about 16 are included in this review. This study have clinical trial case report, retrospective study, prospective study and observational study. The most commonly reported medicine in this systematic review was HCQ, CQ, Azitromycine, immunoglobin and convulscence plasma and ivermectin and doxycycline. Conclusion: This study has considered many study and concluded as HCQ and Azitromycine is having tendency to become patient negative for COVID -19 and there is Convulscence plasma and Immunoglobin is usefull in severely COVID -19 infected patient.
