The aim of this work was to assess the heavy metal environmental pollution in Ouagadougou and its suburban, in order to evaluate the risks on the population health. Lettuce samples, tap and surface waters sample were analyzed to determine the total heavy metal content. The Inductive Coupled Plasma-Spectrometry was used to analyze the samples. The concentration of Cr and Ni at Boulbi were 37.94ppm and 11.00ppm respectively and 8.19ppm of Pb in Baskuy sample. The Cr concentration in Boulbi lettuce was very high than the toxicity thresholds fixed by WHO and concentration of Ni was within the toxicity rang fixed by WHO. The higher value of Pb can lead to health risk due to the bioaccumulation effect. The concentration of Al, Ba, Cu, Fe, As and Cr were low et less than the standards set by WHO. In addition, Massili water was more polluted than Loumbila dam water. Massili water contains Co which is not found in Loumbila dam water. In addition, the concentration of Fe and Mn in water exceeded the recommended standards for irrigation water. The results of this study showthe presence of heavy metals in water and lettuce, andthe degree of risk of consumer.