In dentistry the paradigm has shifted from repair to regeneration. This is possible using various regenerative procedures. Over the years, newer approaches in surgical regenerative procedures have evolved, Platelet Rich Fibrin (PRF) or second generation platelet concentrate is an autologous material containing all the constituents of a blood sample which are favorable to healing and immunity is one such approach. When compared to the use of Platelet Rich Plasma (PRP), PRF has advantages that; it is simplified, cost effective, promotes effective cell migration, cell proliferation etc. This case report highlights the role of Platelet Rich Fibrin, and benefits it offers to future of interdisciplinary approach in promoting guided tissue regeneration using membrane.
