Extraction of oil from African oil bean seed (Pentaclethra macrophylla) was, effected by soxhlet extraction using n-hexane and the extracted oil was, found to be brownish yellow with percentage yield of 38.09%. The extracted oil, analyzed for its proximate, elemental compositions and physicochemical properties, revealed presence of, lipid, moisture and protein at 53.14%, 46.86% and 13.44% respectively for proximate analysis while elemental contents included such minerals as, Mg, Fe, K, Na and small traces of lead (pb). Characterization of the oil shows the acid value as 1.40mg/KOH g-1, peroxide18.0 mEq, iodine 84.84 mg/100g and saponification value 193.12 mg/100g. Anti-microbial screening of the oil was, investigated on six pathogenic microorganisms as, Candida albican, Bacillus cereus, Klesiella pneumoniae, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. 0.1ml of the seed oil was found to inhibit growth of four out of the six-tested organisms including E. coli, S. auerus, C. albicans and B. cereus. Pharmaceutical screening as observed especially with the proximate and elemental compositions indicated medicinal implications of the extracted P.macrophylla oil.
