The possibility to drive the membrane redoxy potential three state dependent 9 stepped full cycle of proton conductance in the favourable direction became a more clear after making the new interpretation relating to eighth and ningh stages of closed 9 staged cycle of proton, electron conductance. The new interpretation as follows as Ninth stage - of 9 staged close cycle of proton conductance in the location of Respiratory membrane, Pulmonary circuit have been distinguished by oxygen uptake from alveolar air -under effect of increase of bicarbonate entry by bicarbonate / chloride ion shift mechanism and gives the possibility to drive and regulate the intensity of proton flow dependent metabolism reaction during diabetes mellitus and hypercholesterinemia to more usefull needed direction because we elucidate in which place of cells are existed driving point of regulations subjected to action of such kinds of manipulation and medicaments.