A Rare Case of Neonatal Sepsis due to Staphylococcus Kloosii in a Late-Preterm Infant with Congenital Heart Defects

Neonatal sepsis is a significant cause of morbidity, with most cases attributed to common pathogens. However, infections caused by atypical, animal-associated organisms, such as Staphylococcus kloosii, pose unique diagnostic and management challenges. This report highlights a late-preterm infant born to a diabetic mother with multiple congenital cardiac anomalies who developed sepsis due to this unexpected organism. Notably, this case represents the first documented neonatal infection and the third overall human case of Staphylococcus kloosii infection, with the previous two cases reported in elderly patients.