A review on “how exactly diuretic drugs are working in our body”

Diuretics are among the most commonly used drugs. They act by diminishing sodium reabsorption at different sites in the nephron, thereby increasing urinary sodium and water losses. The ability to induce negative fluid balance has made diuretics useful in the treatment of a variety of conditions, particularly edematous states and hypertension. A review on physiology of kidney, nephron, urine formation, diuretic drugs with their classification and the mechanism of various diuretics are discussed here with neatly described schematic diagrams.