A field experiment was laid out with the three replications in IVT, four replications in AVT and single row of three meters each of two hundred Germplasms was conducted at the All India Coordinated Research Project (AICRP) on oilseeds at Niger Research Station (NRS), Vanarasi, Navsari, Gujarat on the screening of different elite materials against the two major diseases of niger crop (Guizotia abyssinica Cass). Significantly differences in resistance to all the diseases were found in the elite material tested under natural condition. Results revealed that all the lines of IVT, AVT and germplasms the disease score of Alternaria and Cercospora may vary between 1.0 to 3.0 grade respectively. This study concludes that screening of elite lines of Niger for resistance to diseases is an important factor in developing varieties/hybrids with improved resistance to different diseases.