Studies on the anti-inflammatory activity of schiff base derived compounds

Two Schiff bases were synthesized from raceacetophenone: 1) ADS1: 4-ethyl-6-{(E)-1-[(3-nitrophenyl) imino] ethyl} benzene-1, 3-diol and 2) ADS3: 4-ethyl- 6-{(E)-1-[(2-nitrophenyl) imino] ethyl} benzene-1, 3-diol. Then their metal complexes were formed. The metals ions selected for the synthesis of new complexes were Ruthenium and Copper. These complexed Schiff based derived compounds were evaluated for antiinflammatory activity by carragenean induced ratpaw odema method in rats.