Introduction: A large number of people frequently exposed to unavoidable noise in urban areas, industries, household appliances in this modern world in our daily life. Noise is one of the globally faced environment stressor, which was proved affecting the psycho physiological problems, auditory defect, non-auditory disorder. Objective: Triphalawas selected for this study to understand its efficacy on the membrane bound enzymes of brain during noise exposure. Materials and methods: In this study, wistar strain albino rats were subjected to the four groups, Control, Triphala (which is a combination of three fruits by name (Terminalia chebula, Terminalia bellerica, Emblica officinalis), Noise stress (100dB/4h/ 15 d) and noise stress+Triphla and incubated for 15 days. After 15 days of incubation to noise stress, estimation of Sodium Potassium, Magnesium and Calcium ATPases were evaluated to determine the changes in the membrane bound enzymes of brain. Result and discussion: Administration of the Triphala had a normalizing action on membranes of the cell and controlled the alteration of membrane bound enzymes due to noise stress in noise stress+Triphala group. Conclusion: Therefore treatment with Triphala prevented the decrease in the levels of membrane bound enzymes.
