Acanthocephalans are endoparasites in the gut of vertebrates and have greater importance as they infect wild animals. The prevalence of Pallisentis ophiocephali, was examined in fish, Channa striatus for a period of two annual cycles to determine the effects of seasonal variation on intensity and incidence of infection. The statistical evaluation of difference between different seasons of two annual cycles (2012-2014). Parasites were prevalent throught the year but showed variation in different seasons. These changes may be due to temperature, sex, immunity of host, developmental stages of parasite, feeding habits of host and availability of intermediate hosts.The infection was single or in association with others. The results are discussed in relation to seasonal variation. The results were analyzed by student t-test (P<0.05).