Historically, plants have been preferred over animals in making of human medicine. Abundant transcripts are available sharing various reasons from spiritual believe to regional cultural diversities in accepting plant products and by-products as human medicines. Thus, huge untapped potential of utilization of animal and animal by-products can be explored in making human medicines. Efforts have been made to understand “Role of Animal and its contribution in Human Medicine” as well as potential economical contribution. Liberalization and modernization has shown positive inclination towards animal made medicines due to effective results and healing potential to several diseases. Interestingly, India is one of the world’s potential contributors of animal products, and by-products. Future potential employment, values and opportunities for entrepreneurs, and investor has been explored. Animal seems to play a vital role as a pivot point in growing Indian economy for years to come. It is next to impossible to oversee the animal role in making Human Medicine for a healthy mankind.