Objective: To evaluate antimicrobial activity of Phyllanthus amarus plant extract against resistant pathogenic bacterial strains. Methods: Aqueous and acetone extract of Phyllanthus amarus (Family: Euphorbiaceae) was studied against resistant pathogenic bacterial strains (Bacillus subtilis, Staphylococcus aureus, Enterococcus fecalis, Salmonella typhi, Salmonella paratyphi B, Proteus vulgaris and Serratia marsescens) by disc diffusion method comparable to that of a standard antibacterial Lomefloxacin. Result: Aqueous extract showed 57% efficiency in inhibiting the pathogenic isolates while acetone extract showed 29% efficiency. Conclusion: Phyllanthus amarus aqueous extract was found to be antimicrobially more effective than the acetone extract.
