Hepatitis E virus (HEV) is an important enteric human pathogen worldwide distribution. It can cause sporadic cases as well as large epidemics of acute hepatitis. Many studies proved that HEV infection in pregnancy in the first trimester leads to miscarriage and in the third trimester poor maternal and fetal outcome. Study aimed to determine the prevalence of HEV among miscarriage women attending Saudi Hospital for in Khartoum, during the period from September to December 2019. A total of 70 aborted women .Blood specimens were collected and serum analyzed using Immuno chromatographic test (ICT) IgG and IgM, Enzyme-Linked Immunosorbent Assay (ELISA) for detection of HEV Anti HEV IgM. A total of 70 miscarriage women were included in the study. 5 (7.1%) were positive for anti-HEV IgG and ICT (IgM), while 65 (92.9%) were negative for anti-HEV IgG and ICT (IgM), and were negative for anti-HEV IgM by ELISA, there was insignificant relationship on seroprevalence HEV IgM (positive>1.1).The high prevalence noted among age group 21 – 40years for ICT IgG and IgM. All of the participants (miscarriage women)were analyzed platelets which range from 155 to 432 cell/cubic milliliter.
