QUICK RESPONSE

QUICK RESPONSE WHATSAPP ONLY

              

CATEGORIES

CERTIFICATE

COPYRIGHT AGREEMENT

 

Browse by Subject

  • Agricultural Sciences
  • Biology and Life Sciences
  • Chemistry & Chemical Engineering
  • Medicine, Health & Food
  • Physics
  • Materials Science
  • Mathematics & Statistics
  • Electrical & Computer Science
  • Earth, Energy & Environment
  • Architecture & Civil Engineering
  • Transportation & Logistics
  • Engineering & Technology
  • Economics & Management
  • Education
  • Social Sciences & Psychology
  • Arts, Literature & Linguistics

 

8 Gy single fraction of radiation in brain metastasis: Single institution experience

  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter.inc on line 607.
  • strict warning: Declaration of views_handler_filter::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter.inc on line 607.
  • strict warning: Declaration of views_handler_filter_boolean_operator::value_validate() should be compatible with views_handler_filter::value_validate($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter_boolean_operator.inc on line 159.
  • strict warning: Declaration of views_plugin_row::options_validate() should be compatible with views_plugin::options_validate(&$form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_row.inc on line 134.
  • strict warning: Declaration of views_plugin_row::options_submit() should be compatible with views_plugin::options_submit(&$form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_row.inc on line 134.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_plugin_style_default::options() should be compatible with views_object::options() in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_style_default.inc on line 24.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_handler_argument::init() should be compatible with views_handler::init(&$view, $options) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_argument.inc on line 744.
Author: 
Dr. Nabila Javed, Dr. Javed Iqbal, Dr. Noorul Ain, Dr. Muhammad Rauf Khattak, Dr. Zainab Jan, Dr. Naheed Ahmad, Mr. Habib Ahmad, Dr. Rawail Ahmad and Dr. Khadija Afzal
Abstract: 

Brain metastasis develops in 20-40 % of diagnosed cancer patients worldwide during the course of their illness and represent most frequent neurological complications of systemic cancer as a major cause of morbidity and mortality. The cornerstones of treatment for metastatic brain disease are surgery, whole brain radiotherapy (WBRT) and radio surgery along with varying doses of steroids. As majority of patients present with multiple brain lesions which precludes the option of surgical resection and trials using various systemic chemotherapeutic agents have only demonstrated efficacy in treating brain metastases in a very selected group of primary cancers that are highly chemo sensitive. Whereas radiotherapy has been shown to be effective in treating brain metastases regardless of primary. Commonly used palliative whole brain radiation therapy treatment protocols are 30 Gy in 10 fractions and 20Gy in 05 fraction by two lateral parallel opposed fields. As most of the patients with brain metastases are with poor performance status, this retrospective study was carried out at IRNUM from 1st Jan 2016 –Dec 2016 to evaluate the efficacy of 8 Gy single fraction of radiation to whole brain in terms of relief of symptoms and median as well as overall survival. There were 21 patients .04 male and 18 females. Out of 21 included patients 14 patients were of breast cancer, 06 patients were of lung cancer and 01 patient was of gestational trophoblastic disease. All patients were diagnosed on contrast enhanced Magnetic resonance imaging (CEMRI). All patients were having multiple brain metastases. All patients were planned for whole brain radiotherapy to dose of 08 Gy single fraction by two parallel opposed lateral fields on Co-60 teletherapy machine plus steroids. Patients were monitored for relief of symptoms, median as well as overall survival.

EDITOR-IN-CHIEF

 

               Prof. Dr. ISMAIL YILDIRIM

CALL FOR PAPERS

CURRENT ISSUE

 

IMPACT FACTOR CERTIFICATE