UGC APPROVED JOURNAL

     

CATEGORIES

CERTIFICATE

COPYRIGHT AGREEMENT

 

Browse by Subject

  • Agricultural Sciences
  • Biology and Life Sciences
  • Chemistry & Chemical Engineering
  • Medicine, Health & Food
  • Physics
  • Materials Science
  • Mathematics & Statistics
  • Electrical & Computer Science
  • Earth, Energy & Environment
  • Architecture & Civil Engineering
  • Transportation & Logistics
  • Engineering & Technology
  • Economics & Management
  • Education
  • Social Sciences & Psychology
  • Arts, Literature & Linguistics

 

Antibacterial potency of the combined extracts of Ocimum gratissimum and antibiotics against salmonella typhi and salmonella paratyphi

  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter.inc on line 607.
  • strict warning: Declaration of views_handler_filter::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter.inc on line 607.
  • strict warning: Declaration of views_handler_filter_boolean_operator::value_validate() should be compatible with views_handler_filter::value_validate($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter_boolean_operator.inc on line 159.
  • strict warning: Declaration of views_plugin_row::options_validate() should be compatible with views_plugin::options_validate(&$form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_row.inc on line 134.
  • strict warning: Declaration of views_plugin_row::options_submit() should be compatible with views_plugin::options_submit(&$form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_row.inc on line 134.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_plugin_style_default::options() should be compatible with views_object::options() in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_style_default.inc on line 24.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_handler_argument::init() should be compatible with views_handler::init(&$view, $options) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_argument.inc on line 744.
Author: 
Zumbes, H.J., Babalola, O.B., Yahaya, G.S., Azi, H.Y., Zakari, H., Gokir, J.D. and Dabo, A.D.
Abstract: 

The study assessed the antibacterial effect of the extracts of Ocimumgratissimum and their combined effect with antibiotic drugs against Salmonella Typhi and Salmonella Paratyphi respectively. The extract of Ocimumgratissimum were prepared using Soxhlet apparatus for ethanol and petroleum ether extract, and hot water percolation for aqueous extracts. The antibacterial activities of the plant extracts, the inhibitory effect to some antibiotic drugs; Ciprofloxacin, Gentamycin, Rifampicin, Erythromycin, Chloramphenicol and Ampiclox as well as their combined effect with the antibiotics were evaluated using the disk diffusion method. The inhibitory zones were recorded in millimeters. Phytochemical analysis of the extract were as well carried using standard procedure. The result of this study showed that the hot water extract showed higher antibacterial activities against S. Typhi and S. Paratyphi respectively, followed by the ethanol extract. The petroleum extract however had the least antibacterial effect at the concentration used. All the antibiotic used had greater inhibitory activities on the test organisms except chloramphenicol that showed partial inhibition against S. Typhi. The result also showed that the combined effect of the plant extracts and antibiotics used showed additive interaction against the test isolates. The result of the phytochemical analysis revealed the presence of some secondary metabolites such as flavonoids, carbohydrates, tannins, alkaloids and steroids and terpenes. The findings of this study therefore validate the antibacterial properties of Ocimumgratissimum and its possession of some active compounds as well as its concomitant use with conventional antibiotics to treat many bacterial infections. It is recommended that the in vivo toxicological activity of the plant be evaluated to determine the real effectiveness and potential toxic effects.

EDITOR-IN-CHIEF

 

               Prof. Dr. ISMAIL YILDIRIM

CALL FOR PAPERS

CURRENT ISSUE

 

IMPACT FACTOR CERTIFICATE