The study was undertaken on the clinical cases of wounds in caprine presented at Teaching Veterinary Clinical Complex, Parbhani and area around the vicinity of Parbhani city. A total of 12 clinical cases of lacerated wounds in caprine were studied for the evaluation of 5% ointment of Terminalia arjuna compared with 5% povidone ointment. These clinical cases were divided in to two groups comprised of six cases in each group, irrespective of the type of wound, location, age, sex, breed and body weight. All the cases were observed carefully for the effect of both the treatment in each group. Clinico-pathological observations were recorded on 0, 5th and 10th day, respectively. Haematological and biochemical estimations were carried out by collecting blood samples and serum on 0, 5th and 10th day in each group. Microbiological estimation was carried out by collecting wound swab on 0, 5th and 10th day, respectively. Histopathological and histochemical study was carried out by collecting tissue samples of wound on 0, 7th and 21st day, respectively. The quality of wound healing was measured on the basis of reduction in wound area and wound contraction percentage. The mean values of percentage wound contraction in all cases of both the groups were recorded. Reduction in wound area percentage and rate of wound contraction percentage in group B was found statistically highly significant on day 5 and 10 on compared group A. Haematological values such as Hb, PCV, TLC, TEC and ESR were within normal physiological range, except eosinophil count was significantly increased on day 5 and day 10 in group B while monocyte count was decreased on day 5. However, in biochemical study the total serum protein values were decreased on day 5 which were within normal physiological range. Antimicrobial activity of T. arjuna ointment showed that there was decrease in microbial load in wounds treated on 0, 5th and 10th day compared to wounds treated with povidone ointment. Histopathological and histochemical observations revealed comparatively better results in wound healing with epithelialization, neovascularisation and collagen development, than povidone ointment treated group. From the above observations it concluded that 5% methanolic extract of bark of T. arjuna had better wound healing ability in caprine compared to 5% povidone ointment.
