Aim and Objectives: The aim of this study was to compare the efficacy ofticagrelor + aspirin and clopidogrel + aspirin in the treatment of coronary artery disease and to study the ffectiveness of antiplatelet agents by evaluating the laboratory investigation like ECG, X-ray, 2D-ECHO ,cardiac enzymes, blood test, cardiac catheterization. Materials and Methods: A prospective randomized observational study was conducted in coronary artery disease patients (from 30 years to 70 years of age) to compare the efficacy of two antiplatelets in the department of cardiology Durgabai Deshmukh Hospital. The study conducted for a period of six months from September 2019 to March 2020. Results: Among the total number of patients 80, ticagrelor + aspirin was prescribed to 40 patients whereas remaining 40 administered ticagrelor + aspirinirrespective of their age,sex . The efficacy of drugs is assessed basedevaluating the laboratory investigation like ECG, X-ray, 2D-ECHO ,cardiac enzymes, blood test, cardiac catheterization By comparing all the resultsticagrelor + aspirin showed more efficacy compared toticagrelor + aspirin in all the factors .The efficacy in decreasing frequency is calculated by one-way Annova method whereas hospital stay duration calculated by using T-test. Conclusion: In this study, we compared the efficacy of ticagrelor+aspirin versus clopidogrel+ aspirin in the treatment of coronary artery disease and we compared between both drugs that which drug is given more to the CAD patients.and the result is that more efficacy is seen in patients receiving ticagrelor +aspirin drug and most of the CAD patients are treated with ticagrelor+aspirin drug then compared with clopidogrel+ aspirin drug.
