QUICK CONTACT

 

CATEGORIES

UGC Approved Journal

   .

IMPACT FACTOR CERTIFICATE

Differential immunoreaction of proliferation biomarkers in canine mammary mixed tumors

  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter.inc on line 607.
  • strict warning: Declaration of views_handler_filter::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter.inc on line 607.
  • strict warning: Declaration of views_handler_filter_boolean_operator::value_validate() should be compatible with views_handler_filter::value_validate($form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_filter_boolean_operator.inc on line 159.
  • strict warning: Declaration of views_plugin_row::options_validate() should be compatible with views_plugin::options_validate(&$form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_row.inc on line 134.
  • strict warning: Declaration of views_plugin_row::options_submit() should be compatible with views_plugin::options_submit(&$form, &$form_state) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_row.inc on line 134.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_plugin_style_default::options() should be compatible with views_object::options() in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/plugins/views_plugin_style_default.inc on line 24.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Non-static method view::load() should not be called statically in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/views.module on line 906.
  • strict warning: Declaration of views_handler_argument::init() should be compatible with views_handler::init(&$view, $options) in /home4/vibu/public_html/journalajst.com/sites/all/modules/views/handlers/views_handler_argument.inc on line 744.
Author: 
Daniel A. Viana, José N. Pinto, Glayciane B. Morais, Ana C.L. Pacheco, Conceição S. Martins, Alceu M. Sousa, Gerly Anne C. Brito, Janaína S.A.M. Evangelista, Maria I.F. Guedes and Lúcia D.M. Silva
Abstract: 

Mammary Mixed tumors are one of the most common tumor types in the female canine mammary glands. These tumors exhibit a histological pattern comprising epithelium and mesenchyme, with or without metaplasia, all of them with the capacity to undergo malignant transformation. In most studies, attention is paid to the epithelial component. We analysed the expression of Ki-67, p53 and the presence of AgNORs/nucleus in 17 Benign Mixed Tumors (BMT) and 17 Carcinoma Mixed Type (CMT) using a specific approach of individual tissue elements (epithelial, mesenchymal and cartilage) through tissue microarrays. Ki-67 immunoreaction was nuclear and perinuclear with low intensity but significantly different in epithelial and mesenchymal tissue.p53 had no immunoreaction in any subset of tumors. The AgNOR/nucleus counting was significant lower in the epithelial component of BMT and CMT. However, there was no variation in AgNOR/nucleus count in mesenchymal and cartilage components.

EDITOR-IN-CHIEF

        

            Prof. Dr. ISMAIL YILDIRIM

CURRENT ISSUE

 

COPYRIGHT AGREEMENT