This design study focuses on the care of hypertension among normal weight patients and obese at the Regional Hospital of Ngaoundéré by a regular dietary supplement of Moringa oleifera.The main purpose of this study was to put into evidence the hypotensive properties of Moringa oleifera.Sixty (60) hypertensive patients aged between 28 to 57 years participated to the study. Obtained results showed that obese patients draws a greater benefit of the dietary supplementation of Moringa oleifera than normal weight patients. Obese patients gain more than normal weight patients as regard to the diastolic blood pressure (we observe a reduction value of 14.63 mmHg in the obese group and 6.23 mmHg among normal weight patients). Concerning the values of the systolic blood pressure in obese and normal weight patients, we observed a reduction value of 10.53 mmHg among the normal weight patients and6.86 mmHg among obese patient. These results suggest the existence of elements in the leaves of Moringa oleifera, which may possess hypotensive properties in its composition.