The significance of release from gout pain in Biochemic body caused by limitation of precipitation of uric acid by allopurinol has been measured through physicochemical study. Here, we have carried out the density (ρ), viscosity (η) and UV-Vis measurements of allopurinol in w1= 0.00001, 0.00002 and 0.00003 mass fraction of aqueous uric acid binary mixtures at T= 298.15K, 303.15K, 308.15K, 313.15K. These measurements have been performed to ternary mixture (allopurinol+uric acid+water) to develop some important parameters, namely, limiting apparent molar volume (φV0), viscosity B-coefficients from extended Masson equation and Jones-Dole equation respectively. The refractive index (nD) has been calculated on the same ternary mixtures at T=298.15K. Lorentz-Lorenz equation has used to evaluate molar refractive index (RM) and limiting molar index (RM0). Nature of interaction is determined from UV-Visible spectroscopy. These parameters have been interpreted in terms of interactions of solute itself and with solvent.
