Periodontal regenerative procedure is a surgical therapy that aims to make up new bone, radicular cement, periodontal ligament (identified as new periodontal attack), demonstrated by histologic studies. The damage of these periodontal tissues is an effect of periodontal disease or occlusal trauma. Histologically, the new attachment is different from the long epithelial attachment. This occurs when there is migration of the junctional epithelium instead of connective tissue. Both preclinical and clinical studies proved that periodontal regeneration can be successful using surgical procedures, that may or may not involve membranes or grafting materials. The present study describes the clinicopathological features of 5 patients with clinical and histopathological confirmation of periodontal disease, predominantly located into the zona of two inferior central incisors, which has determined the bone reabsorption of the bone peaks. This, ultimately, provided unesthetic spaces between the teeth. The results of the surgical therapy practiced in this case, were assessed by clinical and radiological control, to ensure correct resolution of the case.
