Cigarette smoking is the leading cause of preventable diseases and premature death. Smoking can increase the risk of cardiovascular disease, respiratory disease, and 10 different forms of cancer. Cigarette smoking is said to be responsible for over 25 diseases in humans some of which include chronic bronchitis, ischaemic heart disease and cancers of the lung, oral cavity, urinary bladder, pancreas, and larynx. Smokers also face a much greater risk of premature death than non-smokers. Cigarette smoking is an important risk factor for periodontal disease. Cigarette smoking is considered to be the single most important factor responsible for the high prevalence of cancer and for death related to cancer. The aim of this study was to review the literature on knowledge and attitudes of ill-effects of smoking.