The overall aim of this study was to determine the prevalence of co-infection of typhoidal salmonellosis and schistosomiasis amongst selected subject groups in zone A geopolitical zone of Benue State Nigeria. Five locations were randomly selected and they were: Iange, Sati, Korgyen, Ikov Sati and Adikpo. A total of 180 subjects were studied. Two clinical samples (urine and stool) were collected from each subject following standard medical laboratory practices and guidelines. A total of 360 clinical samples were investigated using microscopic, cultural and biochemical methods. Salmonellacul ture, isolation and biochemical tests were carried out from faecal samples. Schistosomiasis was diagnosed through the detection of parasite eggs in stool for S. mansoni or urine specimens for S. haematobium. Computation was done for: total Salmonella infection and Salmonella-schistosomiasisco-infection. There were 25 cases of Salmonella infection out of 180 samples thus resulting in prevalence of 13.89% in zone A axis of Benue State. Prevalence per sampling distribution across the communities from highest to lowest are: Ikov Sati (21.67%), Adikpo (15%), Sati (11.1%) and Iange (4.76%). No Salmonella cases were recorded at Korgyen community among 21 samples. Sex status revealed 36% male and 64% female. Occupational status showed 60% farmers as the most infected group, 12% each for student and marketers and 8% each for civil servants and okada riders. Age group 21-30 years were the most vulnerable as they constituted 32% of the infected subjects. Age group 1-10 years was 1% while 61-70 years had no salmonella cases. There were 8 cases of Salmonella-schistosomiasis co-infections out of 180 samples with a total prevalence of 4.44% in the study area. Across the communities, Iange and Korgyen had no co-infection cases while Adikpo had the highest number of 5 with a prevalence of 8.33%. followed by Sati (5.55%). Male and female had equal proportion of co-infection cases while farming was the highest (50%) among the occupational type and Age group 21-30 was the highest (38%) among the age groups. The information given in this report is vital in the control of Salmonella and its co-infections with schistosomiasis in the study area.
