We report the case of a 2-year-old child with no history especially access the service at the age of one month for intraocular retinoblastoma unilat right. Then eighten months later there was a location in the left eye. The patient is seen 20 months later with large bilateral tumors of both orbits extending towards the zeugmatic area on right and the front left area. Oculars structures are covered with two larges chemosis. The objective brain scan large tumor in the brain. The treatment consisted of chemotherapy with Vincristine-Adriblastine-Cyclophosphamide-Etoposide protocol. After sixth treatment we found a significant decrease in tumor volume. Then child is lost.
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